Is This Die off Reaction?

by Thalia


I just started feeding my 7 yr old German Shepard Ketona Naturals 3 days ago to hopefully help with a yeast infection (itchy ears & chin, licking paws).

I noticed today that she is leaking urine while she is lying down.

I’m curious if this could be caused by die off reaction. She doesn’t seem to be in pain and is acting normally.

Would love to hear your thoughts on this.

Thank you,

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Jan 26, 2023
Think my dog is having the same reaction!
by: Tracy

Going to try and make this short. One of my dogs has a yeast problem, so we switched to ketona to try and help, and have been giving to both dogs for about 2 weeks. Shortly after we switched, we had a urine leaking incident, also while sleeping. We thought it was our girl (3yo, non yeast problem) and that she had a uti. After $600 at the vet to run a battery of tests because there is no uti, we decided maybe it was our other dog leaking as we were wrong initially about who was leaking. After another $200 spent today for urine test and exam for him (no uti either), the vet is saying we should think about whether it could be the ketona (some ingredient therein) since this started shortly after we switched to it. Can't say forsure, of course, but my search for ketona and incontinence brought me here. Curious if there are more who have experienced the same reaction?

Nov 24, 2022
Die Off Reaction or Something Else
by: Sandra

Hello Thalia,

Sorry for the late reply.

At the time you wrote to me, you had only switched food 3 days ago. That is surely not enough time to cause a detox reaction of any kind, in my opinion.

Since your dog is 7yo and female, it would be my thought that the urine leakage could be hormone related.

If she were my dog, I would give it a bit of time, perhaps 2 or 3 weeks, to see if the incontinence clears up, or gets worse.

A visit to the vet may be in order here.


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